KDM5A

Across TCGA patient cohorts, KDM5A RNA expression is significantly associated with the protein abundance of many other proteins, with 8,878 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible KDM5A-associated proteins across cancer lineages are SIN3A, SMC1A, and EFTUD2. Each is linked with KDM5A in more than 4 cancer types. Because this analysis shows association rather than direction, both KDM5A-to-partner and partner-to-KDM5A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KDM5A versus SIN3A in BRCA, with a Pearson correlation of 0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KDM5A→partner) and Y-score (partner→KDM5A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SIN3A →	+0.199	+0.410	<.001	<.001	3	5
BRCA	SMC1A →	+0.230	+0.382	.002	.009	3	5
LSCC	EFTUD2 →	+0.245	+0.599	<.001	<.001	3	5
HNSC	HNRNPL →	+0.226	+0.894	<.001	<.001	3	5
HNSC	HNRNPLL →	+0.264	+0.726	<.001	<.001	3	5
LSCC	ATN1_T669 →	+0.709	+0.451	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,878 associations by consensus.

KDM5A vs SIN3A — BRCA

Explore this scatter interactively →