KDM4E

Across TCGA patient cohorts, KDM4E RNA expression is significantly associated with the go_rna of many other GO terms, with 6,941 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible KDM4E-associated GO terms across cancer lineages are Nuclear-transcribed mRNA catabolic process, TOR signaling, and Vacuole organization. Each is linked with KDM4E in more than 19 cancer types. Because this analysis shows association rather than direction, both KDM4E-to-partner and partner-to-KDM4E results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nuclear-transcribed mRNA catabolic process grouped by KDM4E-low versus KDM4E-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KDM4E→partner) and Y-score (partner→KDM4E) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Nuclear-transcribed mRNA catabolic process →	+0.061	+0.057	<.001	<.001	3	20
STAD	TOR signaling →	+0.057	+0.055	<.001	<.001	3	19
STAD	Vacuole organization →	+0.059	+0.062	<.001	<.001	3	19
STAD	Transcription by RNA polymerase III →	+0.041	+0.040	<.001	<.001	3	19
STAD	Endosomal transport →	+0.059	+0.060	<.001	<.001	3	19
STAD	Negative regulation of TOR signaling →	+0.056	+0.052	<.001	<.001	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,941 associations by consensus.

Nuclear-transcribed mRNA catabolic process by KDM4E expression — STAD

Explore this box plot interactively →