KDM4E

Across TCGA cell cohorts, KDM4E protein abundance is significantly associated with the go_rna of many other GO terms, with 778 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible KDM4E-associated GO terms across cancer lineages are Somatic diversification of immunoglobulins involved in immune response, Positive regulation of mesenchymal cell proliferation, and NK T cell activation. Each is linked with KDM4E in more than 3 cancer types. Because this analysis shows association rather than direction, both KDM4E-to-partner and partner-to-KDM4E results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Somatic diversification of immunoglobulins involved in immune response grouped by KDM4E-low versus KDM4E-high in SOFT_TISSUE.

protein abundance associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KDM4E→partner) and Y-score (partner→KDM4E) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Somatic diversification of immunoglobulins involved in immune response →	+0.141	+2.104	<.001	.002	2	4
KIDNEY	Positive regulation of mesenchymal cell proliferation →	+0.172	+1.548	.002	.005	3	3
KIDNEY	NK T cell activation →	+0.233	+1.548	<.001	.005	3	3
BLOOD_Leukemia	Nephron tubule development →	+0.166	+1.329	.002	.003	3	3
STOMACH	Glutathione derivative biosynthetic process →	+0.225	+1.857	.006	.003	2	4
OESOPHAGUS	Synaptic vesicle lumen acidification →	-0.137	-1.384	.005	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 778 associations by consensus.

Somatic diversification of immunoglobulins involved in immune response by KDM4E expression — SOFT_TISSUE

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