Across TCGA patient cohorts, KDM4D RNA expression is significantly associated with the protein abundance of many other proteins, with 16,567 significant associations in total. GBM shows the largest number of these associations.

The most reproducible KDM4D-associated proteins across cancer lineages are FAM76B_S193, PARP4_S1186, and HDAC2. Each is linked with KDM4D in more than 5 cancer types. Because this analysis shows association rather than direction, both KDM4D-to-partner and partner-to-KDM4D results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KDM4D→partner) and Y-score (partner→KDM4D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	FAM76B_S193 →	+0.597	+0.403	<.001	<.001	3	6
GBM	PARP4_S1186 →	-0.789	-0.329	<.001	<.001	3	5
HNSC	HDAC2 →	+0.325	+0.664	<.001	<.001	3	5
LSCC	SSRP1 →	+0.489	+0.499	<.001	<.001	3	5
HNSC	CCDC82_S131 →	+0.688	+0.655	<.001	<.001	3	5
GBM	CWC15 →	+0.302	+0.273	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,567 associations by consensus.

Exploration

KDM4D survival (RNA) · tumor vs normal (RNA) · all KDM4D data types