KDM4C

Across TCGA patient cohorts, KDM4C protein abundance is significantly associated with the protein abundance of many other proteins, with 14,542 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible KDM4C-associated proteins across cancer lineages are KDM3A, CDCA7L, and HAUS3. Each is linked with KDM4C in more than 3 cancer types. Because this analysis shows association rather than direction, both KDM4C-to-partner and partner-to-KDM4C results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KDM4C versus KDM3A in HNSC, with a Pearson correlation of 0.64.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KDM4C→partner) and Y-score (partner→KDM4C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	KDM3A →	+0.664	+0.934	<.001	.001	3	4
BRCA	CDCA7L →	+1.503	+0.774	<.001	<.001	3	3
CCRCC	HAUS3 →	+0.485	+0.782	<.001	<.001	3	3
GBM	KDM4B →	+0.512	+0.575	<.001	<.001	3	3
HNSC	SPIN1_S199 →	+0.633	+0.922	<.001	<.001	2	3
BRCA	NOTCH1 →	+0.998	+0.756	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,542 associations by consensus.

KDM4C vs KDM3A — HNSC

Explore this scatter interactively →