KDM4B

Across TCGA cell cohorts, KDM4B mutation is significantly associated with the RNA expression of many other genes, with 1,476 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KDM4B-associated genes across cancer lineages are ANKRD54, TNRC6B, and TRMU. Each is linked with KDM4B in more than 1 cancer types. Because this analysis shows association rather than direction, both KDM4B-to-partner and partner-to-KDM4B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ANKRD54 grouped by KDM4B-low versus KDM4B-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KDM4B→partner) and Y-score (partner→KDM4B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ANKRD54 →	+0.516	+3.936	<.001	<.001	3	2
LARGE_INTESTINE	TNRC6B →	+0.728	+3.523	<.001	<.001	3	2
LARGE_INTESTINE	TRMU →	+0.568	+2.043	.001	.008	3	2
LARGE_INTESTINE	ZBED4 →	+0.578	+3.459	<.001	.001	3	2
LARGE_INTESTINE	PPP4R3A →	+0.432	+2.129	.002	.007	3	2
LARGE_INTESTINE	PRPS2 →	+0.512	+3.169	.005	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,476 associations by consensus.

ANKRD54 by KDM4B expression — LARGE_INTESTINE

Explore this box plot interactively →