KDM4A

Across TCGA patient cohorts, KDM4A RNA expression is significantly associated with the protein abundance of many other proteins, with 11,055 significant associations in total. GBM shows the largest number of these associations.

The most reproducible KDM4A-associated proteins across cancer lineages are SRSF9, MBD3, and ERI3. Each is linked with KDM4A in more than 4 cancer types. Because this analysis shows association rather than direction, both KDM4A-to-partner and partner-to-KDM4A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KDM4A versus SRSF9 in LSCC, with a Pearson correlation of 0.44.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KDM4A→partner) and Y-score (partner→KDM4A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SRSF9 →	+0.478	+0.486	<.001	<.001	3	5
LSCC	MBD3 →	+0.492	+0.470	<.001	.004	3	5
OV	ERI3 →	+0.376	+0.744	<.001	<.001	3	5
OV	TRIM28 →	+0.380	+0.504	<.001	.001	3	5
GBM	HNRNPLL →	+0.275	+0.305	<.001	<.001	3	4
GBM	KHDRBS1 →	+0.245	+0.269	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,055 associations by consensus.

KDM4A vs SRSF9 — LSCC

Explore this scatter interactively →