KDM2B

Across TCGA cell cohorts, KDM2B mutation is significantly associated with the RNA expression of many other genes, with 1,303 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KDM2B-associated genes across cancer lineages are ZC3H14, MTFMT, and CUEDC2. Each is linked with KDM2B in more than 1 cancer types. Because this analysis shows association rather than direction, both KDM2B-to-partner and partner-to-KDM2B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZC3H14 grouped by KDM2B-low versus KDM2B-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KDM2B→partner) and Y-score (partner→KDM2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ZC3H14 →	+0.491	+2.000	<.001	.009	3	2
LARGE_INTESTINE	MTFMT →	+0.506	+1.850	.001	.006	3	2
LARGE_INTESTINE	CUEDC2 →	+0.603	+2.364	<.001	<.001	3	2
LARGE_INTESTINE	MYH3 →	+0.541	+1.850	.001	.006	3	2
LARGE_INTESTINE	CRACD →	+0.778	+2.364	.007	<.001	3	2
LARGE_INTESTINE	ACYP1 →	+0.425	+1.850	.008	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,303 associations by consensus.

ZC3H14 by KDM2B expression — LARGE_INTESTINE

Explore this box plot interactively →