KDM1A

Across TCGA patient cohorts, KDM1A protein abundance is significantly associated with the RNA expression of many other genes, with 21,730 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible KDM1A-associated genes across cancer lineages are PIK3CG, JAML, and ATP8B4. Each is linked with KDM1A in more than 8 cancer types. Because this analysis shows association rather than direction, both KDM1A-to-partner and partner-to-KDM1A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KDM1A versus PIK3CG in LSCC, with a Pearson correlation of -0.54.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KDM1A→partner) and Y-score (partner→KDM1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PIK3CG →	-0.958	-0.307	<.001	<.001	3	9
LSCC	JAML →	-0.927	-0.267	<.001	<.001	3	9
OV	ATP8B4 →	-0.682	-0.230	<.001	<.001	3	8
LSCC	BTK →	-0.858	-0.320	<.001	<.001	3	8
LSCC	MS4A6A →	-0.813	-0.280	<.001	<.001	3	8
LSCC	CD180 →	-0.879	-0.334	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,730 associations by consensus.

KDM1A vs PIK3CG — LSCC

Explore this scatter interactively →