KDM1A

Across TCGA cell cohorts, KDM1A RNA expression is significantly associated with the go_rna of many other GO terms, with 5,530 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KDM1A-associated GO terms across cancer lineages are DNA strand elongation involved in DNA replication, Double-strand break repair via break-induced replication, and Positive regulation of attachment of mitotic spindle microtubules to kinetochore. Each is linked with KDM1A in more than 15 cancer types. Because this analysis shows association rather than direction, both KDM1A-to-partner and partner-to-KDM1A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA strand elongation involved in DNA replication grouped by KDM1A-low versus KDM1A-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KDM1A→partner) and Y-score (partner→KDM1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	DNA strand elongation involved in DNA replication →	+0.157	+1.015	<.001	<.001	3	16
BONE	Double-strand break repair via break-induced replication →	+0.248	+1.384	.004	.001	3	15
OESOPHAGUS	Positive regulation of attachment of mitotic spindle microtubules to kinetochore →	+0.194	+1.073	.003	<.001	3	15
OESOPHAGUS	Microtubule cytoskeleton organization involved in mitosis →	+0.131	+1.136	.002	<.001	3	15
OESOPHAGUS	Mitotic spindle elongation →	+0.274	+1.235	.002	<.001	3	15
OESOPHAGUS	Mitotic spindle midzone assembly →	+0.274	+1.235	.002	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,530 associations by consensus.

DNA strand elongation involved in DNA replication by KDM1A expression — BONE

Explore this box plot interactively →