KDF1

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, KDF1 protein abundance is significantly associated with the RNA expression of many other genes, with 9,620 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible KDF1-associated genes across cancer lineages are CLEC10A, GYPC, and CLEC4E. Each is linked with KDF1 in more than 4 cancer types. Because this analysis shows association rather than direction, both KDF1-to-partner and partner-to-KDF1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KDF1 versus CLEC10A in HNSC, with a Pearson correlation of -0.32.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KDF1→partner) and Y-score (partner→KDF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCCLEC10A →-0.971-0.404.003.00235
OVGYPC →-1.130-0.746<.001<.00135
HNSCCLEC4E →-0.932-0.380<.001.00135
HNSCGIMAP8 →-0.967-0.458<.001.00135
HNSCSELL →-1.346-0.521<.001<.00135
HNSCTRAJ19 →-1.491-0.421.008.00635
Each partner links to its Q-omics profile. Showing the 6 strongest of 9,620 associations by consensus.

KDF1 vs CLEC10A — HNSC

Per-sample scatter of KDF1 vs CLEC10A in HNSC (Pearson r = -0.32).

Explore this scatter interactively →

Exploration