KDF1

Across TCGA cell cohorts, KDF1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,327 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible KDF1-associated GO terms across cancer lineages are Response to molecule of fungal origin, Cellular response to molecule of fungal origin, and Desmosome maintenance. Each is linked with KDF1 in more than 11 cancer types. Because this analysis shows association rather than direction, both KDF1-to-partner and partner-to-KDF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to molecule of fungal origin grouped by KDF1-low versus KDF1-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KDF1→partner) and Y-score (partner→KDF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Response to molecule of fungal origin →	+1.651	+2.500	<.001	<.001	3	12
LUNG_NSCLC_LUSC	Cellular response to molecule of fungal origin →	+1.651	+2.500	<.001	<.001	3	12
OVARY	Desmosome maintenance →	+1.585	+2.333	<.001	<.001	3	12
OVARY	Sensory perception of salty taste →	+1.631	+1.996	<.001	<.001	3	12
LUNG_NSCLC_LUAD	Positive regulation of endothelial cell development →	+0.290	+2.500	<.001	<.001	3	11
LUNG_NSCLC_LUAD	Positive regulation of establishment of endothelial barrier →	+0.290	+2.500	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,327 associations by consensus.

Response to molecule of fungal origin by KDF1 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →