KDELR2

Across TCGA patient cohorts, KDELR2 protein abundance is significantly associated with the RNA expression of many other genes, with 13,609 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible KDELR2-associated genes across cancer lineages are YBX3, GAPDHP1, and PBOV1. Each is linked with KDELR2 in more than 7 cancer types. Because this analysis shows association rather than direction, both KDELR2-to-partner and partner-to-KDELR2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KDELR2 versus YBX3 in BRCA, with a Pearson correlation of 0.71.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KDELR2→partner) and Y-score (partner→KDELR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	YBX3 →	+1.156	+0.588	<.001	<.001	3	8
BRCA	GAPDHP1 →	+1.355	+0.526	.001	<.001	3	5
UCEC	PBOV1 →	-0.827	-0.324	.001	.002	3	5
GBM	CLDN5 →	-0.785	-0.359	.001	.001	3	4
LSCC	MAGOHB →	+0.673	+0.439	<.001	<.001	3	4
COAD	MRPL51 →	+0.603	+0.305	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,609 associations by consensus.

KDELR2 vs YBX3 — BRCA

Explore this scatter interactively →