KDELR2

Across TCGA patient cohorts, KDELR2 mutation is significantly associated with the RNA expression of many other genes, with 1,014 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KDELR2-associated genes across cancer lineages are RNU2-8P, RN7SL379P, and LINC02173. Each is linked with KDELR2 in more than 1 cancer types. Because this analysis shows association rather than direction, both KDELR2-to-partner and partner-to-KDELR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU2-8P grouped by KDELR2-low versus KDELR2-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KDELR2→partner) and Y-score (partner→KDELR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RNU2-8P →	+0.512	+7.741	<.001	.009	3	2
LGG	RN7SL379P →	+0.124	+7.977	<.001	.007	3	2
LGG	LINC02173 →	+0.069	+7.977	<.001	.007	3	2
LGG	MRPS17P5 →	+0.159	+7.977	<.001	.007	3	2
COAD	ZYXP1 →	+0.705	+7.741	<.001	.009	3	2
COAD	MIR8074 →	+0.886	+7.741	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,014 associations by consensus.

RNU2-8P by KDELR2 expression — COAD

Explore this box plot interactively →