KDELR2

Across TCGA patient cohorts, KDELR2 mutation is significantly associated with the immune_cell of many other genes, with 14 significant associations in total. COAD shows the largest number of these associations.

The most reproducible KDELR2-associated genes across cancer lineages are Erythrocytes, CD8+ T-cells, and CD8+ Tcm. Each is linked with KDELR2 in more than 1 cancer types. Because this analysis shows association rather than direction, both KDELR2-to-partner and partner-to-KDELR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Erythrocytes grouped by KDELR2-low versus KDELR2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KDELR2→partner) and Y-score (partner→KDELR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Erythrocytes →	+0.028	+2.241	.012	.031	3	2
COAD	CD8+ T-cells →	+0.029	+6.142	<.001	.027	3	1
COAD	CD8+ Tcm →	+0.044	+5.917	<.001	.032	3	1
COAD	Fibroblasts →	+0.066	+5.721	<.001	.036	3	1
COAD	Monocytes →	+0.035	+6.734	<.001	.018	3	1
COAD	Tregs →	+0.122	+6.409	<.001	.023	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

Erythrocytes by KDELR2 expression — UCEC

Explore this box plot interactively →