KDELR1

Across TCGA pan-cancer cohorts, KDELR1 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated KDELR1 data layer compared with 22 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in ovarian serous cystadenocarcinoma (OV), where higher KDELR1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated KDELR1 expression acts as an unfavorable survival marker.

OV, HNSC, and CCRCC are the cancer types where KDELR1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
OV	DFS	Median	All	0.857	1.000	.038	4	view →
HNSC	DFS	Median	III,IV	0.659	0.898	.016	3	view →
CCRCC	DFS	Median	II,III,IV	0.762	1.000	.044	1	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

KDELR1–OV (DFS)

Open the OV breakdown →