KDELR1

Across TCGA cell cohorts, KDELR1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,867 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible KDELR1-associated GO terms across cancer lineages are COPII-coated vesicle cargo loading, Protein retention in ER lumen, and Maintenance of protein localization in endoplasmic reticulum. Each is linked with KDELR1 in more than 13 cancer types. Because this analysis shows association rather than direction, both KDELR1-to-partner and partner-to-KDELR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, COPII-coated vesicle cargo loading grouped by KDELR1-low versus KDELR1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KDELR1→partner) and Y-score (partner→KDELR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	COPII-coated vesicle cargo loading →	+0.111	+0.541	.005	.001	3	14
BLOOD_Myeloma	Protein retention in ER lumen →	+0.129	+1.229	<.001	<.001	3	10
BLOOD_Lymphoma	Maintenance of protein localization in endoplasmic reticulum →	+0.119	+0.895	<.001	<.001	3	10
BREAST	Regulation of natural killer cell mediated cytotoxicity directed against tumor cell target →	+0.283	+0.828	<.001	<.001	3	10
BLOOD_Leukemia	Positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target →	+0.679	+0.462	.005	<.001	3	10
SKIN	COPII-coated vesicle budding →	+0.080	+0.592	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,867 associations by consensus.

COPII-coated vesicle cargo loading by KDELR1 expression — BONE

Explore this box plot interactively →