KDELR1

Across TCGA cell cohorts, KDELR1 mutation is significantly associated with the mutation status of many other genes, with 763 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KDELR1-associated genes across cancer lineages are PEX7, TBX18, and PDGFRB. Each is linked with KDELR1 in more than 1 cancer types. Because this analysis shows association rather than direction, both KDELR1-to-partner and partner-to-KDELR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PEX7 grouped by KDELR1-low versus KDELR1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KDELR1→partner) and Y-score (partner→KDELR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	PEX7 →	+5.329	+4.672	<.001	<.001	1	2
LARGE_INTESTINE	TBX18 →	+3.329	+3.799	.005	.005	1	2
LARGE_INTESTINE	PDGFRB →	+2.744	+4.321	.002	.002	1	2
LARGE_INTESTINE	NCL →	+3.744	+4.044	.003	.003	1	2
BLOOD_Leukemia	HELLS →	+6.321	+6.321	.001	.001	1	2
BLOOD_Leukemia	ZSCAN20 →	+4.736	+5.560	.003	.003	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 763 associations by consensus.

PEX7 by KDELR1 expression — LARGE_INTESTINE

Explore this box plot interactively →