KCTD4

Across TCGA patient cohorts, KCTD4 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,148 significant associations in total. GBM shows the largest number of these associations.

The most reproducible KCTD4-associated proteins across cancer lineages are RBM26, ZSWIM8_S567, and KPNA3. Each is linked with KCTD4 in more than 3 cancer types. Because this analysis shows association rather than direction, both KCTD4-to-partner and partner-to-KCTD4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KCTD4 versus RBM26 in LSCC, with a Pearson correlation of 0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KCTD4→partner) and Y-score (partner→KCTD4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RBM26 →	+0.258	+0.421	.001	.001	3	4
CCRCC	ZSWIM8_S567 →	-0.455	-0.255	<.001	.007	3	4
PDAC	KPNA3 →	+0.292	+0.242	<.001	<.001	3	4
PDAC	SPCS3 →	-0.431	-0.325	<.001	<.001	3	3
PDAC	TOP2B_S1413 →	+0.749	+0.278	.003	.004	3	3
GBM	NPTN →	+0.498	+0.406	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,148 associations by consensus.

KCTD4 vs RBM26 — LSCC

Explore this scatter interactively →