KCTD4

Across TCGA patient cohorts, KCTD4 protein abundance is significantly associated with the RNA expression of many other genes, with 2,943 significant associations in total. GBM shows the largest number of these associations.

The most reproducible KCTD4-associated genes across cancer lineages are EDIL3, CASKIN2, and GRK3. Each is linked with KCTD4 in more than 1 cancer types. Because this analysis shows association rather than direction, both KCTD4-to-partner and partner-to-KCTD4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KCTD4 versus EDIL3 in BRCA, with a Pearson correlation of 0.54.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCTD4→partner) and Y-score (partner→KCTD4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	EDIL3 →	+2.036	+1.469	.001	.006	3	2
BRCA	CASKIN2 →	+1.079	+1.201	.001	.003	3	2
GBM	GRK3 →	+0.659	+0.836	<.001	<.001	3	1
GBM	PIK3IP1 →	+0.768	+0.737	<.001	<.001	3	1
GBM	SOX10 →	+1.607	+0.842	<.001	<.001	3	1
GBM	SLC16A8 →	+0.716	+0.793	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,943 associations by consensus.

KCTD4 vs EDIL3 — BRCA

Explore this scatter interactively →