KCTD4

Across TCGA cell cohorts, KCTD4 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,006 significant associations in total. CNS shows the largest number of these associations.

The most reproducible KCTD4-associated GO terms across cancer lineages are Regulation of plasminogen activation, Negative regulation of plasminogen activation, and Negative regulation of dendritic cell apoptotic process. Each is linked with KCTD4 in more than 5 cancer types. Because this analysis shows association rather than direction, both KCTD4-to-partner and partner-to-KCTD4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of plasminogen activation grouped by KCTD4-low versus KCTD4-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KCTD4→partner) and Y-score (partner→KCTD4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Regulation of plasminogen activation →	+0.190	+0.767	<.001	.008	3	6
OVARY	Negative regulation of plasminogen activation →	+0.392	+0.531	<.001	.003	3	6
OVARY	Negative regulation of dendritic cell apoptotic process →	+0.904	+0.525	<.001	.003	3	6
CNS	PML body organization →	+0.100	+1.113	<.001	<.001	3	5
OVARY	Regulation of potassium ion transport →	+0.136	+0.531	<.001	.003	3	5
CNS	Regulation of wound healing →	+0.083	+1.077	<.001	.009	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,006 associations by consensus.

Regulation of plasminogen activation by KCTD4 expression — OVARY

Explore this box plot interactively →