KCTD20

Across TCGA cell cohorts, KCTD20 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. CNS shows the largest number of these associations.

The most reproducible KCTD20-associated genes across cancer lineages are TBC1D3, OR2H1, and OR52B2. Each is linked with KCTD20 in more than 1 cancer types. Because this analysis shows association rather than direction, both KCTD20-to-partner and partner-to-KCTD20 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TBC1D3 grouped by KCTD20-low versus KCTD20-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCTD20→partner) and Y-score (partner→KCTD20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	TBC1D3 →	+0.080	+4.273	<.001	.006	3	1
CNS	OR2H1 →	+0.035	+5.321	<.001	.005	3	1
CNS	OR52B2 →	+0.048	+4.981	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

TBC1D3 by KCTD20 expression — LARGE_INTESTINE

Explore this box plot interactively →