KCTD2

Across TCGA patient cohorts, KCTD2 protein abundance is significantly associated with the RNA expression of many other genes, with 1,533 significant associations in total. GBM shows the largest number of these associations.

The most reproducible KCTD2-associated genes across cancer lineages are HBS1L, STK26, and SEC11C. Each is linked with KCTD2 in more than 2 cancer types. Because this analysis shows association rather than direction, both KCTD2-to-partner and partner-to-KCTD2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KCTD2 versus HBS1L in BRCA, with a Pearson correlation of -0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCTD2→partner) and Y-score (partner→KCTD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	HBS1L →	-0.592	-0.475	.001	.006	3	3
BRCA	STK26 →	-1.363	-0.697	.003	<.001	3	3
UCEC	SEC11C →	-0.998	-0.411	.002	.002	3	2
UCEC	LINC01504 →	+0.791	+0.606	.001	.004	3	2
CCRCC	SDHDP4 →	-0.590	-0.339	.006	<.001	3	2
BRCA	EPRS1 →	-0.552	-0.559	.004	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,533 associations by consensus.

KCTD2 vs HBS1L — BRCA

Explore this scatter interactively →