KCTD17

Across TCGA patient cohorts, KCTD17 mutation is significantly associated with the total protein of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KCTD17-associated genes across cancer lineages are EGFR_pY1068, VHL, and DJ-1. Each is linked with KCTD17 in more than 1 cancer types. Because this analysis shows association rather than direction, both KCTD17-to-partner and partner-to-KCTD17 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, EGFR_pY1068 grouped by KCTD17-low versus KCTD17-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCTD17→partner) and Y-score (partner→KCTD17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EGFR_pY1068 →	-0.250	-3.000	.048	.036	3	1
UCEC	VHL →	-0.973	-2.321	.004	.035	3	1
UCEC	DJ-1 →	+0.237	+2.820	.004	.035	3	1
UCEC	p62 Lck ligand →	+0.399	+3.009	.014	.019	2	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

EGFR_pY1068 by KCTD17 expression — UCEC

Explore this box plot interactively →