KCTD17

Across TCGA cell cohorts, KCTD17 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KCTD17-associated genes across cancer lineages are MAGEB4, SLC15A5, and KRTAP4-1. Each is linked with KCTD17 in more than 1 cancer types. Because this analysis shows association rather than direction, both KCTD17-to-partner and partner-to-KCTD17 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MAGEB4 grouped by KCTD17-low versus KCTD17-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCTD17→partner) and Y-score (partner→KCTD17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	MAGEB4 →	+0.012	+5.415	.009	.004	3	1
LARGE_INTESTINE	SLC15A5 →	+0.023	+5.415	<.001	.004	3	1
BLOOD_Lymphoma	KRTAP4-1 →	+0.151	+4.867	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

MAGEB4 by KCTD17 expression — LARGE_INTESTINE

Explore this box plot interactively →