KCTD17

Across TCGA cell cohorts, KCTD17 mutation is significantly associated with the mutation status of many other genes, with 795 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible KCTD17-associated genes across cancer lineages are PARP12, USP16, and SCUBE2. Each is linked with KCTD17 in more than 2 cancer types. Because this analysis shows association rather than direction, both KCTD17-to-partner and partner-to-KCTD17 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PARP12 grouped by KCTD17-low versus KCTD17-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCTD17→partner) and Y-score (partner→KCTD17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	PARP12 →	+4.429	+5.247	.005	.005	1	3
BLOOD_Lymphoma	USP16 →	+6.014	+6.014	.001	.001	1	3
BLOOD_Lymphoma	SCUBE2 →	+4.429	+5.247	.005	.005	1	3
BLOOD_Lymphoma	LIMK2 →	+4.429	+5.247	.005	.005	1	3
LARGE_INTESTINE	PPP2R5B →	+4.523	+5.087	.006	.006	1	2
BLOOD_Lymphoma	KRIT1 →	+5.014	+5.584	.003	.003	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 795 associations by consensus.

PARP12 by KCTD17 expression — BLOOD_Lymphoma

Explore this box plot interactively →