Across TCGA patient cohorts, KCTD16 protein abundance is significantly associated with the RNA expression of many other genes, with 10,505 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible KCTD16-associated genes across cancer lineages are ASPA, SLC4A10, and KCND3. Each is linked with KCTD16 in more than 2 cancer types. Because this analysis shows association rather than direction, both KCTD16-to-partner and partner-to-KCTD16 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCTD16→partner) and Y-score (partner→KCTD16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ASPA →	+0.899	+0.546	<.001	<.001	3	3
GBM	SLC4A10 →	+1.027	+0.577	<.001	<.001	3	3
PDAC	KCND3 →	+0.741	+0.401	.002	<.001	3	3
GBM	GALNTL6 →	+0.444	+0.808	<.001	<.001	3	3
GBM	ATP1A2 →	+1.388	+0.452	<.001	<.001	3	3
LSCC	ADH1B →	+1.768	+0.565	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,505 associations by consensus.

Exploration

KCTD16 survival (RNA) · tumor vs normal (RNA) · all KCTD16 data types