Across TCGA patient cohorts, KCTD16 mutation is significantly associated with the RNA expression of many other genes, with 2,713 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KCTD16-associated genes across cancer lineages are ALMS1-IT1, RNU5E-9P, and RPS8P6. Each is linked with KCTD16 in more than 2 cancer types. Because this analysis shows association rather than direction, both KCTD16-to-partner and partner-to-KCTD16 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCTD16→partner) and Y-score (partner→KCTD16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ALMS1-IT1 →	+0.322	+3.021	.001	<.001	3	3
LUSC	RNU5E-9P →	+0.099	+3.868	<.001	.009	3	3
BLCA	RPS8P6 →	+0.108	+3.628	<.001	.006	3	3
HNSC	RPS29P32 →	+0.655	+5.505	<.001	.004	3	3
SKCM	GOLGA6L10 →	+0.254	+2.161	<.001	.002	3	2
LIHC	RNU6-786P →	+0.366	+4.771	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,713 associations by consensus.

Exploration

KCTD16 survival (RNA) · tumor vs normal (RNA) · all KCTD16 data types