KCTD16

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, KCTD16 mutation is significantly associated with the total protein of many other genes, with 39 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KCTD16-associated genes across cancer lineages are Annexin-1, ASNS, and C-Raf. Each is linked with KCTD16 in more than 1 cancer types. Because this analysis shows association rather than direction, both KCTD16-to-partner and partner-to-KCTD16 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCTD16→partner) and Y-score (partner→KCTD16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECAnnexin-1 →+0.599+2.827.001.00132
UCECASNS →+0.413+2.000<.001.00932
UCECC-Raf →+0.136+1.440.006.02432
UCEC14-3-3_beta →-0.074-1.973.032.02931
UCECEGFR_pY1068 →-0.306-3.807<.001<.00131
UCECeIF4E →+0.177+3.183.015.00931
Each partner links to its Q-omics profile. Showing the 6 strongest of 39 associations by consensus.

Exploration