Across TCGA cell cohorts, KCTD16 mutation is significantly associated with the RNA expression of many other genes, with 12 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KCTD16-associated genes across cancer lineages are IQCF6, IQCF5, and RBMY1A1. Each is linked with KCTD16 in more than 1 cancer types. Because this analysis shows association rather than direction, both KCTD16-to-partner and partner-to-KCTD16 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCTD16→partner) and Y-score (partner→KCTD16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	IQCF6 →	+0.210	+3.297	<.001	.002	3	2
OVARY	IQCF5 →	+0.197	+5.339	<.001	<.001	3	1
OVARY	RBMY1A1 →	+0.107	+4.807	<.001	.003	3	1
CNS	CFC1B →	+0.013	+6.357	<.001	<.001	3	1
CNS	S100G →	+0.272	+5.321	<.001	.005	3	1
CNS	OR5H2 →	+0.040	+5.321	.003	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

Exploration

KCTD16 survival (RNA) · tumor vs normal (RNA) · all KCTD16 data types