KCTD14

Across TCGA pan-cancer cohorts, KCTD14 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated KCTD14 data layer compared with 25 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher KCTD14 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated KCTD14 expression acts as an unfavorable survival marker, although some lineages such as HNSC and CCRCC show a favorable association.

HNSC, CCRCC, and UCEC are the cancer types where KCTD14 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Median	All	1.000	0.484	.038	12	view →
CCRCC	OS	Median	III,IV	0.985	0.237	.017	9	view →
UCEC	DFS	Quartile	All	0.982	0.808	.017	6	view →
LSCC	DFS	Median	II,III,IV	0.553	0.854	.014	4	view →
PDAC	OS	Median	IV	0.491	0.836	.024	3	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

KCTD14–HNSC (OS)

Open the HNSC breakdown →