KCTD14

Across TCGA patient cohorts, KCTD14 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,395 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible KCTD14-associated proteins across cancer lineages are PLEKHA6_S459, PLXDC2, and APOE. Each is linked with KCTD14 in more than 3 cancer types. Because this analysis shows association rather than direction, both KCTD14-to-partner and partner-to-KCTD14 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KCTD14 versus PLEKHA6_S459 in LSCC, with a Pearson correlation of 0.52.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KCTD14→partner) and Y-score (partner→KCTD14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PLEKHA6_S459 →	+0.939	+0.510	<.001	<.001	3	3
UCEC	PLXDC2 →	-0.386	-0.787	<.001	.001	2	4
CCRCC	APOE →	-0.647	-0.621	<.001	<.001	3	3
CCRCC	MXRA5 →	-0.907	-0.671	.001	.001	3	3
UCEC	NFIB_S312 →	+0.663	+0.744	.001	<.001	3	3
LSCC	DIP2B →	-0.477	-0.609	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,395 associations by consensus.

KCTD14 vs PLEKHA6_S459 — LSCC

Explore this scatter interactively →