KCTD14

Across TCGA cell cohorts, KCTD14 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,320 significant associations in total. BONE shows the largest number of these associations.

The most reproducible KCTD14-associated GO terms across cancer lineages are PML body organization, Positive regulation of cytoskeleton organization, and Aorta smooth muscle tissue morphogenesis. Each is linked with KCTD14 in more than 7 cancer types. Because this analysis shows association rather than direction, both KCTD14-to-partner and partner-to-KCTD14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PML body organization grouped by KCTD14-low versus KCTD14-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KCTD14→partner) and Y-score (partner→KCTD14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	PML body organization →	+0.291	+2.878	<.001	<.001	3	8
BONE	Positive regulation of cytoskeleton organization →	+0.073	+1.431	.001	.001	3	8
LUNG_NSCLC_LUSC	Aorta smooth muscle tissue morphogenesis →	+1.323	+2.153	.002	.002	3	8
URINARY_TRACT	Regulation of intracellular protein transport →	+0.068	+1.268	<.001	.005	3	8
BONE	Negative regulation of dendritic cell apoptotic process →	+1.322	+1.173	<.001	.001	3	8
BONE	Viral process →	+0.100	+1.347	<.001	.002	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,320 associations by consensus.

PML body organization by KCTD14 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →