KCTD14

Across TCGA cell cohorts, KCTD14 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KCTD14-associated genes across cancer lineages are ECE2, CENPVL1, and CENPVL3. Each is linked with KCTD14 in more than 1 cancer types. Because this analysis shows association rather than direction, both KCTD14-to-partner and partner-to-KCTD14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ECE2 grouped by KCTD14-low versus KCTD14-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCTD14→partner) and Y-score (partner→KCTD14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ECE2 →	+0.319	+4.054	<.001	.004	3	1
LARGE_INTESTINE	CENPVL1 →	+0.169	+4.510	<.001	.001	3	1
LARGE_INTESTINE	CENPVL3 →	+0.194	+3.920	<.001	.005	3	1
LARGE_INTESTINE	SCN11A →	+0.198	+3.772	<.001	.007	2	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

ECE2 by KCTD14 expression — LARGE_INTESTINE

Explore this box plot interactively →