KCTD13

Across TCGA patient cohorts, KCTD13 mutation is significantly associated with the RNA expression of many other genes, with 655 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KCTD13-associated genes across cancer lineages are MIR5190, RNA5SP357, and TRAJ43. Each is linked with KCTD13 in more than 1 cancer types. Because this analysis shows association rather than direction, both KCTD13-to-partner and partner-to-KCTD13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR5190 grouped by KCTD13-low versus KCTD13-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCTD13→partner) and Y-score (partner→KCTD13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	MIR5190 →	+0.818	+5.080	.006	.008	3	2
UCEC	RNA5SP357 →	+0.598	+1.922	<.001	.007	3	2
UCEC	TRAJ43 →	+0.746	+2.263	<.001	.003	3	2
UCEC	MIR548H3 →	+0.330	+2.714	<.001	.005	3	2
SKCM	SHQ1P1 →	+0.027	+3.730	.004	.008	3	2
SKCM	OR1AA1P →	+0.054	+4.614	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 655 associations by consensus.

MIR5190 by KCTD13 expression — COAD

Explore this box plot interactively →