KCTD12

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, KCTD12 protein abundance is significantly associated with the RNA expression of many other genes, with 18,916 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible KCTD12-associated genes across cancer lineages are HLA-DOA, ATP8B4, and CD33. Each is linked with KCTD12 in more than 8 cancer types. Because this analysis shows association rather than direction, both KCTD12-to-partner and partner-to-KCTD12 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KCTD12 versus HLA-DOA in HNSC, with a Pearson correlation of 0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCTD12→partner) and Y-score (partner→KCTD12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCHLA-DOA →+1.360+0.395<.001<.00139
UCECATP8B4 →+0.792+0.746<.001<.00139
GBMCD33 →+0.639+0.469<.001<.00139
LSCCPIK3CG →+0.952+0.431<.001<.00139
UCECCPED1 →+1.116+0.503<.001<.00139
HNSCCD4 →+0.886+0.367<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 18,916 associations by consensus.

KCTD12 vs HLA-DOA — HNSC

Per-sample scatter of KCTD12 vs HLA-DOA in HNSC (Pearson r = 0.34).

Explore this scatter interactively →

Exploration