Across TCGA patient cohorts, KCTD11 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,524 significant associations in total. GBM shows the largest number of these associations.

The most reproducible KCTD11-associated proteins across cancer lineages are PYGL, AHNAK2, and PPFIBP1. Each is linked with KCTD11 in more than 6 cancer types. Because this analysis shows association rather than direction, both KCTD11-to-partner and partner-to-KCTD11 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KCTD11→partner) and Y-score (partner→KCTD11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	PYGL →	+0.620	+0.781	<.001	<.001	3	7
CCRCC	AHNAK2 →	+0.993	+0.412	<.001	.006	3	7
LSCC	PPFIBP1 →	+0.522	+0.922	<.001	<.001	3	6
LSCC	TNKS1BP1 →	+0.344	+0.739	<.001	<.001	3	5
CCRCC	ENO1 →	+0.342	+0.390	.003	.002	3	5
PDAC	EPB41_S95 →	-0.738	-0.648	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,524 associations by consensus.

Exploration

KCTD11 survival (RNA) · tumor vs normal (RNA) · all KCTD11 data types