KCTD10

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, KCTD10 mutation is significantly associated with the RNA expression of many other genes, with 369 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KCTD10-associated genes across cancer lineages are RN7SKP203, RPL23AP38, and BLOC1S2P1. Each is linked with KCTD10 in more than 1 cancer types. Because this analysis shows association rather than direction, both KCTD10-to-partner and partner-to-KCTD10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SKP203 grouped by KCTD10-low versus KCTD10-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCTD10→partner) and Y-score (partner→KCTD10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CESCRN7SKP203 →+0.189+4.409<.001.00632
BLCARPL23AP38 →+0.616+3.479<.001.00832
BRCABLOC1S2P1 →+0.274+5.441<.001.00532
LGGRNU6-383P →+0.368+7.977<.001.00732
LUSCMTCO3P20 →+0.109+4.530.009.00132
LUSCRN7SL132P →+0.796+4.780<.001.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 369 associations by consensus.

RN7SKP203 by KCTD10 expression — CESC

Box plot of RN7SKP203 in KCTD10-low vs KCTD10-high samples in CESC.

Explore this box plot interactively →

Exploration