KCNV1

Across TCGA patient cohorts, KCNV1 mutation is significantly associated with the total protein of many other genes, with 65 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KCNV1-associated genes across cancer lineages are PCNA, Cyclin-E1, and Annexin_VII. Each is linked with KCNV1 in more than 3 cancer types. Because this analysis shows association rather than direction, both KCNV1-to-partner and partner-to-KCNV1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PCNA grouped by KCNV1-low versus KCNV1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNV1→partner) and Y-score (partner→KCNV1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PCNA →	+0.207	+2.087	.004	.005	3	4
COAD	Cyclin-E1 →	+0.327	+2.467	.002	.011	3	3
SKCM	Annexin_VII →	-0.158	-1.678	.005	.022	3	3
UCEC	MEK1 →	+0.398	+1.874	.001	.002	3	3
UCEC	ATM →	-0.638	-2.893	<.001	.001	3	3
UCEC	Cyclin-B1 →	+0.562	+2.201	.002	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 65 associations by consensus.

PCNA by KCNV1 expression — UCEC

Explore this box plot interactively →