KCNV1

Across TCGA pan-cancer cohorts, KCNV1 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of KCNV1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where KCNV1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types KCNV1 is over-expressed in tumor, although a few such as COAD and KICH show the opposite, repressed pattern.

KIRP, COAD, and KIRC are the cancer types where KCNV1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in KCNV1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRP	Male	II,III,IV	+2.242	<.001	11	view →
COAD	Female	All	−0.642	<.001	8	view →
KIRC	Male	All	+0.415	<.001	7	view →
KICH	Male	All	−0.353	<.001	7	view →
LUAD	All	All	+0.327	<.001	7	view →
THCA	Female	All	+0.380	<.001	6	view →
LUSC	All	All	+0.196	.017	2	view →
PAAD	All	All	−0.077	.009	2	view →
PRAD	All	All	−0.011	.041	2	view →
LIHC	All	All	+0.005	.023	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

KCNV1–KIRP

Open the KIRP breakdown →