KCNV1

Across TCGA cell cohorts, KCNV1 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,403 significant associations in total. BONE shows the largest number of these associations.

The most reproducible KCNV1-associated GO terms across cancer lineages are Positive regulation of cell junction assembly, Action potential, and Cholesterol metabolic process. Each is linked with KCNV1 in more than 5 cancer types. Because this analysis shows association rather than direction, both KCNV1-to-partner and partner-to-KCNV1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of cell junction assembly grouped by KCNV1-low versus KCNV1-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNV1→partner) and Y-score (partner→KCNV1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Positive regulation of cell junction assembly →	-0.145	-1.112	<.001	.001	3	6
OVARY	Action potential →	-0.091	-0.421	<.001	<.001	3	6
BONE	Cholesterol metabolic process →	+0.106	+0.286	<.001	.006	2	6
CNS	Presynaptic active zone organization →	-0.139	-0.079	<.001	.002	3	5
LUNG_NSCLC_LUSC	Regulation of MDA-5 signaling pathway →	+0.137	+0.845	.003	.006	3	5
BONE	Coronary vasculature development →	-0.106	-0.355	.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,403 associations by consensus.

Positive regulation of cell junction assembly by KCNV1 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →