KCNV1

Across TCGA cell cohorts, KCNV1 mutation is significantly associated with the RNA expression of many other genes, with 33 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible KCNV1-associated genes across cancer lineages are COX6A2, H1-8, and ETDB. Each is linked with KCNV1 in more than 1 cancer types. Because this analysis shows association rather than direction, both KCNV1-to-partner and partner-to-KCNV1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, COX6A2 grouped by KCNV1-low versus KCNV1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNV1→partner) and Y-score (partner→KCNV1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	COX6A2 →	+0.068	+4.022	<.001	.006	3	2
LUNG_SCLC	H1-8 →	+0.071	+3.169	.002	.001	3	2
BLOOD_Leukemia	ETDB →	+0.054	+4.551	<.001	.004	3	2
LUNG_NSCLC_LUAD	OR2L8 →	+0.007	+3.681	<.001	.009	3	2
BLOOD_Lymphoma	DMRTC2 →	+0.009	+4.643	<.001	.005	3	1
BLOOD_Lymphoma	FCN2 →	+0.056	+4.714	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 33 associations by consensus.

COX6A2 by KCNV1 expression — LARGE_INTESTINE

Explore this box plot interactively →