KCNT1

Across TCGA cell cohorts, KCNT1 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,354 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible KCNT1-associated GO terms across cancer lineages are RNA catabolic process, Nucleic acid catabolic process, and Negative regulation of myoblast fusion. Each is linked with KCNT1 in more than 8 cancer types. Because this analysis shows association rather than direction, both KCNT1-to-partner and partner-to-KCNT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA catabolic process grouped by KCNT1-low versus KCNT1-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNT1→partner) and Y-score (partner→KCNT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	RNA catabolic process →	+0.044	+0.156	<.001	.005	3	9
BLOOD_Lymphoma	Nucleic acid catabolic process →	+0.046	+0.160	<.001	.004	3	8
LUNG_SCLC	Negative regulation of myoblast fusion →	+0.094	+1.245	<.001	.006	3	8
STOMACH	Regulation of protein localization to nucleus →	+0.056	+0.316	.008	.009	2	9
LUNG_SCLC	Positive regulation of telomerase RNA localization to Cajal body →	+0.083	+1.492	<.001	<.001	3	7
BLOOD_Lymphoma	Nuclear-transcribed mRNA catabolic process →	+0.042	+0.148	<.001	.009	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,354 associations by consensus.

RNA catabolic process by KCNT1 expression — LARGE_INTESTINE

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