KCNS3

Across TCGA cell cohorts, KCNS3 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KCNS3-associated genes across cancer lineages are GYS2 and TBC1D3. Each is linked with KCNS3 in more than 1 cancer types. Because this analysis shows association rather than direction, both KCNS3-to-partner and partner-to-KCNS3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GYS2 grouped by KCNS3-low versus KCNS3-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNS3→partner) and Y-score (partner→KCNS3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	GYS2 →	+0.047	+3.930	<.001	.003	3	1
LARGE_INTESTINE	TBC1D3 →	+0.066	+4.688	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

GYS2 by KCNS3 expression — LARGE_INTESTINE

Explore this box plot interactively →