Across TCGA pan-cancer cohorts, KCNRG RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated KCNRG data layer compared with 3 for mutation status.
The strongest signal is observed in uveal melanoma (UVM), where higher KCNRG RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated KCNRG expression acts as an unfavorable survival marker, although some lineages such as UCEC and LUAD show a favorable association.
UVM, UCEC, and LUAD are the cancer types where KCNRG RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.