Across TCGA pan-cancer cohorts, KCNRG Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated KCNRG data layer compared with 22 for mass-spec protein.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher KCNRG Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated KCNRG expression acts as an unfavorable survival marker.

KIRP, SKCM, and COAD are the cancer types where KCNRG Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	OS	Median	All	0.272	0.885	<.001	12	view →
SKCM	DFS	Median	All	0.209	0.728	.020	12	view →
COAD	OS	Median	II,III,IV	0.464	0.853	.018	2	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: KCNRG tumor-vs-normal RNA expression · all KCNRG data types