KCNQ5-AS1

Across TCGA pan-cancer cohorts, KCNQ5-AS1 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of KCNQ5-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where KCNQ5-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types KCNQ5-AS1 is over-expressed in tumor, although a few such as THCA and LIHC show the opposite, repressed pattern.

THCA, BRCA, and LUAD are the cancer types where KCNQ5-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in KCNQ5-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	All	All	−0.038	.011	3	view →
BRCA	Female	All	+0.061	.032	2	view →
LUAD	All	All	+0.104	.037	1	view →
LIHC	All	All	−0.006	.029	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

KCNQ5-AS1–THCA

Open the THCA breakdown →