KCNQ1OT1

Across TCGA patient cohorts, KCNQ1OT1 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,522 significant associations in total. GBM shows the largest number of these associations.

The most reproducible KCNQ1OT1-associated proteins across cancer lineages are ADNP, CHPF, and DBN1. Each is linked with KCNQ1OT1 in more than 3 cancer types. Because this analysis shows association rather than direction, both KCNQ1OT1-to-partner and partner-to-KCNQ1OT1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KCNQ1OT1 versus ADNP in GBM, with a Pearson correlation of 0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNQ1OT1→partner) and Y-score (partner→KCNQ1OT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ADNP →	+0.344	+0.570	<.001	<.001	3	4
OV	CHPF →	+0.520	+0.661	<.001	<.001	3	4
GBM	DBN1 →	+0.447	+0.872	<.001	<.001	3	4
HNSC	DGKA →	-0.348	-0.466	<.001	.001	3	4
HNSC	DOCK1 →	+0.284	+0.671	<.001	<.001	3	4
CCRCC	FBLN2 →	+0.578	+0.474	.008	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,522 associations by consensus.

KCNQ1OT1 vs ADNP — GBM

Explore this scatter interactively →