KCNN2

Across TCGA cell cohorts, KCNN2 RNA expression is significantly associated with the RNA expression of many other genes, with 6,702 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KCNN2-associated genes across cancer lineages are ONECUT2, PPFIA1, and PENK. Each is linked with KCNN2 in more than 3 cancer types. Because this analysis shows association rather than direction, both KCNN2-to-partner and partner-to-KCNN2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KCNN2 versus ONECUT2 in LUNG_SCLC, with a Pearson correlation of 0.42.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNN2→partner) and Y-score (partner→KCNN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	ONECUT2 →	+1.404	+1.087	<.001	<.001	3	3
SKIN	PPFIA1 →	+0.803	+1.505	.002	.002	3	3
LUNG_SCLC	PENK →	+2.501	+0.863	<.001	.001	3	3
BLOOD_Leukemia	DUSP3 →	+1.362	+2.043	<.001	<.001	3	3
SKIN	SPOP →	-0.678	-2.070	<.001	<.001	3	3
BLOOD_Leukemia	SLC44A2 →	-1.634	-1.705	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,702 associations by consensus.

KCNN2 vs ONECUT2 — LUNG_SCLC

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