KCNN2

Across TCGA cell cohorts, KCNN2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,903 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KCNN2-associated GO terms across cancer lineages are Regulation of nervous system process, Axonogenesis, and Cardiac muscle cell action potential involved in contraction. Each is linked with KCNN2 in more than 5 cancer types. Because this analysis shows association rather than direction, both KCNN2-to-partner and partner-to-KCNN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of nervous system process grouped by KCNN2-low versus KCNN2-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNN2→partner) and Y-score (partner→KCNN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Regulation of nervous system process →	-0.081	-0.199	<.001	.006	3	6
SKIN	Axonogenesis →	-0.032	-1.534	.001	.001	3	5
LARGE_INTESTINE	Cardiac muscle cell action potential involved in contraction →	-0.112	-0.443	<.001	.006	3	5
BLOOD_Leukemia	Regulation of striated muscle contraction →	-0.061	-1.140	<.001	<.001	3	5
SKIN	Positive regulation of glycoprotein biosynthetic process →	-0.061	-1.152	.002	.004	3	5
SKIN	Negative regulation of sensory perception of pain →	+1.143	+1.515	<.001	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,903 associations by consensus.

Regulation of nervous system process by KCNN2 expression — OESOPHAGUS

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